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采用回顾性队列研究的方法，对合成橡胶行业中４６７名生产和使用苯乙烯的女工和５２７名对照工人进行了生殖流行病学调查。结果表明，接触组女工妊娠恶阻及早产、新生儿出生缺陷的危险度增加且具有统计学意义，其他指标未见差异。
A retrospective cohort study was conducted on the reproductive epidemiology of 467 female workers and 527 control workers in the synthetic rubber industry producing and using styrene. The results showed that female workers in contact group had decreased risk of pregnancy obstruction and premature birth and neonatal birth defects with statistically significant differences, while other indicators did not differ.