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本文研究bepridil对室上速的作用。 13例复发性持续性室上速患者,其中12例曾用过1～3种抗心律失常药无效。开始,5例静脉注射本品4 mg/kg;然后,12例每日口服300～400mg。治疗前后作电生理检查。12例长程治疗,每月复查一次。一律不用其他抗心律失常药。 5例静脉注射后,心房调搏周期(产生房室传导阻滞)由276±43延至334±31 ms(P<0.01),心室调搏周期(产生室房传导阻滞)
This article studies the effect of bepridil on supraventricular tachycardia. Thirteen patients with recurrent persistent supraventricular tachycardia were found to be ineffective in 12 of the 12 patients who used 1 to 3 antiarrhythmic drugs. Beginning, 5 cases of intravenous injection of this product 4 mg / kg; then, 12 cases daily oral administration of 300 ~ 400mg. Before and after treatment for electrophysiological examination. 12 cases of long-term treatment, review once a month. Never use other anti-arrhythmic drugs. After 5 cases of intravenous injection, the atrial pacing cycle (atrioventricular block) was delayed from 276 ± 43 to 334 ± 31 ms (P <0.01)