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目的 探讨通辽市蒙古族、汉族高血压、冠心病人与健康人的血脂水平 ,为防治高血压、冠心病提供科学依据。方法 对通辽地区 4 85例健康人、35 8例高血压病人和 179例冠心病人进行血脂测定。结果 汉族健康人血清胆固醇 (TC)浓度为 (172 0 .5± 4 5 3.4 )mg·L- 1,蒙古族为 (16 33.7± 4 36 .1)mg·L- 1,两者间差异显著 (P <0 .0 5 ) ;汉族血清甘油三酯 (TG)为 (12 2 4 .8±5 31.4 )mg·L- 1,蒙古族为 (897.7± 35 6 .4 )mg·L- 1,两者间差异非常显著 (P <0 .0 1) ;汉族血清高密度脂蛋白胆固醇 (HDL -C)浓度和HDL -C/TC比值分别为 ((5 76 .6± 16 7.9)mg·L- 1和 (32 .4 4±9.6 3) % ,蒙古族为 ((5 6 0 .6± 176 .9)mg·L- 1和 ((33.95± 8.84 ) % ,两者间差异均无统计学意义 (P>0 .0 5 )。蒙古族、汉族TC、TG及HDL -C浓度均与年龄正相关 (r =0 .5 4～ 0 .99,P <0 .0 1)。蒙古族、汉族高血压、冠心病人之TC、TG浓度均高于健康人 (P <0 .0 1) ,而HDL -C和HDL -C/TC比值则明显低于健康人 (P <0 .0 1)。结论 临床除测定TC、TG、HDL -C等血脂项目外 ,还应计算HDL -C/TC比值 ,作为综合评价血脂对动脉硬化影响程度的指标之一
Objective To investigate the blood lipid levels of Mongolian and Han nationality in Tongliao City, Han population with hypertension and coronary heart disease, and to provide scientific basis for the prevention and treatment of hypertension and coronary heart disease. Methods Blood lipid was measured in 4 85 healthy subjects, 358 hypertensive patients and 179 coronary heart disease patients in Tongliao area. Results The levels of serum cholesterol (172.5 ± 45.5) mg · L-1 in healthy Han and (16 33.7 ± 4 36.1) mg · L-1 in Mongolian were significantly different between Han nationality and Han nationality (P <0.05). The level of serum triglyceride (TG) was (122.4 ± 8.51.4) mg · L-1 in Han nationality and (897.7 ± 35.6.4) mg · L-1 in Mongolian nationality (P <0.01). The serum HDL-C and HDL-C / TC ratios in Han nationality were (5 76.6 ± 16 7.9) mg · (34.4 ± 9.63)% for L-1 and (56.6 ± 176.9) mg · L-1 and (33.95 ± 8.84)% for Mongolian, with no difference between the two Statistical significance (P> 0.05). Mongolian and Han nationality TC, TG and HDL-C concentrations were positively correlated with age (r = 0.54 ~ 0.99, P <0.01) The levels of TC and TG in patients with hypertension, coronary heart disease were significantly higher than those in healthy people (P <0.01), while the HDL-C and HDL-C / TC ratios were significantly lower than those in healthy people (P <0. 0 1) .Conclusion In addition to the determination of TC, TG, HDL-C and other blood lipids, the ratio of HDL-C / TC should be calculated as one of the indexes for comprehensive evaluation of the effect of blood lipids on atherosclerosis