本文报告1例局部应用磷酸氮洁霉素并发顽固性梭状芽胞杆菌毒素阳性的伪膜性结肠炎。患者42岁,女性。因严重腹泻、腹痛、发热,伴大量草绿色水样便3天入院。病前6个月内因面部座疮仅间断外用过磷酸氯洁霉素。近期内无住院、旅游及腹泻史,否认口服 This article reports 1 case of topical application of phosphate nitrogen lincomycin combined with intradermal Clostridium toxin-positive pseudomembranous colitis. Patient 42 years old, female. Due to severe diarrhea, abdominal pain, fever, accompanied by a large number of grass-green water samples were admitted to hospital for 3 days. Six months before the disease due to facial acne only intermittent topical use chlorine clindamycin. No recent hospitalization, tourism and diarrhea history, denied oral