目的超声对性早熟女童治疗前后子宫和卵巢变化情况进行测量,探讨彩色多普勒超声在女童性早熟诊断及治疗效果观察中的价值。方法选择2012年1月-2014年1月在镇海区中医医院儿科就诊,临床诊断为性早熟的女童60例为性早熟组,同时选择正常健康女童60例作为对照组,性早熟组女童年龄(6.54±1.21)岁,对照组(6.49±1.18)岁,比较两组女童的子宫、卵巢和卵泡的超声结果。结果性早熟组女童的子宫容积、子宫长径、子宫前后径和子宫宽径均明显大于对照组女童(t=9.345、7.342、4.246、6.342,P均<0.05)。性早熟组女童的卵巢容积、卵巢长径、卵巢前后径和卵巢宽径均明显大于对照组女童(t=5.346、7.164、0.76、4.786,P均<0.05)。性早熟组女童的卵巢卵泡数目和卵泡直径均明显大于对照组女童(t=15.267、9.146,P均<0.05)。性早熟女童治疗后子宫容积和子宫长径明显小于治疗前(t=7.264、6.475,P均<0.05),性早熟女童治疗后卵巢容积和卵巢长径明显小于治疗前(t=6.784、6.543,P均<0.05),性早熟女童治疗后卵泡数量和卵泡直径明显小于治疗前(t=13.154、3.768,P均<0.05)。结论超声检查发现性早熟女童患者的子宫大小、卵巢大小、卵泡数目和卵泡大小均大于健康女童,性早熟女童经过正规治疗后子宫大小、卵巢大小、卵泡数目和卵泡大小均明显缩小,超声检查在女童性早熟的诊断和预后评估中具有重要意义。 Objective To investigate the changes of uterus and ovary in precocious girls before and after treatment, and to explore the value of color Doppler ultrasound in the diagnosis and treatment of precocious puberty in girls. Methods From January 2012 to January 2014, 60 children with clinically diagnosed precocious puberty were selected as precocious puberty group and 60 normal healthy girls as control group. The age of girls with precocious puberty 6.54 ± 1.21) years old, and control group (6.49 ± 1.18) years old. The results of uterus, ovary and follicles were compared between the two groups. The results showed that the volume of uterus, the length of uterus, the anteroposterior diameter of uterus and the width of uterus in girls with precocious puberty were significantly higher than those in the control group (t = 9.345,7.342,4.246,6.342, P <0.05). The volume of ovary, the major axis of ovary, the anteroposterior diameter of ovary and the width of ovary were significantly higher in girls with precocious puberty than those in the control group (t = 5.346,7.164,0.76,4.786, P <0.05). The number of ovarian follicles and follicular diameter in girls with precocious puberty were significantly higher than those in the control group (t = 15.267, 9.146, P <0.05). The precocious girls’ uterine volume and uterine diameter after treatment were significantly less than those before treatment (t = 7.264,6.475, P <0.05). The volume and ovarian diameter of the precocious girls after treatment were significantly lower than those before treatment (t = 6.784,6.543, P <0.05). The number of follicles and the diameter of follicles in girls with precocious puberty were significantly less than those before treatment (t = 13.154, 3.768, P <0.05). Conclusions Uterine size, ovarian size, number of follicles and follicle size in patients with precocious puberty were significantly higher than those in healthy girls. Ultrasonography showed that uterine size, ovarian size, number of follicles and follicular size were significantly reduced after regular treatment. Precocious puberty diagnosis and prognosis of girls is of great significance.