ＡＤ３２ 和ＤＭ 是蒽环类抗肿瘤抗生素，临床上用于治疗难治性膀胱癌、淋巴瘤、间皮瘤、乳癌、卵巢癌、头颈部癌、小细胞肺癌、睾丸癌、骨髓癌、结肠癌、血管肉瘤、子宫颈癌、肝癌等．本文在进行ＡＤ３２ 和ＤＭ 的化学合成和工艺研究的基础上，应用１Ｈ－ １Ｈ ＣＯＳＹ、ＮＯＥＳＹ、１３Ｃ－ １ＨＣＯＳＹ、ＨＭＱＣ和ＨＭＢＣ 等１Ｄ 和２Ｄ ＮＭＲ 技术对它们的氢和碳进行了全归属 AD 32 and DM anthracycline antitumor antibiotics, clinically used for the treatment of refractory bladder cancer, lymphoma, mesothelioma, breast cancer, ovarian cancer, head and neck cancer, small cell lung cancer, testicular cancer, bone marrow cancer , Colon cancer, angiosarcoma, cervical cancer, liver cancer and the like. Based on the chemical synthesis and technology research of AD32 and DM, the hydrogen and carbon have all been assigned to them by 1D and 2D NMR techniques such as 1H-1H COZY, NOESY, 13C-1HCOSY, HMQC and HMBC