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应用肉毒杆菌毒素A(BTX)治疗斜视,是近年来发展起来的一种新的药物疗法。BTX是一种以神经毒性为特征的可溶性强烈毒素,对人体肌肉有很强的麻痹作用。局部注射适量的BTX,可以降低斜视眼外肌的功能,从而引起眼位的改变。经临床观察证明,应用BTX治疗斜视,具有独特的疗效和较为广泛的适应证。本文对这种新疗法的机理、适应证、治疗方法及其并发症等问题进行了综述。
Application of botulinum toxin A (BTX) treatment of strabismus is a new drug therapy developed in recent years. BTX is a strongly soluble toxin characterized by neurotoxicity and has a strong paralytic effect on human muscles. Local injection of appropriate amount of BTX, can reduce the function of strabismic extraocular muscles, causing eye position changes. Clinical evidence shows that the application of BTX treatment of strabismus, has a unique effect and a more extensive indications. This article reviews the mechanisms, indications, treatments and complications of this new therapy.