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目的观察早期胰岛素强化治疗新发2型糖尿病的有效性和安全性。方法 150例新发2型糖尿病的住院患者,按是否愿意接受早期胰岛素强化分为试验组82例和对照组68例,试验组采取早期胰岛素强化治疗,对照组给予吡格列酮片,连续治疗2周后评价效果。结果经过2周治疗后,试验组患者总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、血清脂蛋白(a)[LP(a)]、空腹血糖和餐后2 h血糖的水平均明显高于对照组,差异有统计学意义(P<0.05)。结论早期胰岛素强化治疗新发2型糖尿病具有较好的临床效果。
Objective To observe the efficacy and safety of early insulin therapy in the treatment of newly diagnosed type 2 diabetes mellitus. Methods A total of 150 inpatients with newly diagnosed type 2 diabetes were divided into experimental group (n = 82) and control group (n = 68) according to whether they were willing to receive early insulin. The patients in the experimental group were treated with pioglitazone and were given pioglitazone tablets continuously for 2 weeks Evaluation of the effect. Results After two weeks of treatment, the total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), serum lipoprotein (a) The blood glucose levels at 2 h after meal were significantly higher than those in the control group (P <0.05). Conclusion Early intensive insulin treatment of newly diagnosed type 2 diabetes has a good clinical effect.