在很多情况下,神经系统成为化学物毒作用的一个靶器官,评价化学物质的神经毒性,应了解其毒性的生化机理,然而应用生化方法来测定神经毒性的文献却很少。Barnes于1965年论述了神经病的生化改变,但遗憾的是在以后的12年中,这一领域几乎无进展。近年来, In many cases, the nervous system becomes a target organism for chemical toxicity. To assess the neurotoxicity of chemical substances, the biochemical mechanism of its toxicity should be known. However, there are only a few literatures on biochemical methods to determine neurotoxicity. Barnes addressed the biochemical changes in neuropathy in 1965, but unfortunately in the next 12 years there has been almost no progress in this area. In recent years,