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我们曾报导采用血清Ehrlich呈色反映可作为筛诊癌瘤的一种简易方法,并发现胃癌检出阳性率最高、达78.9％,为进一步评价本法在筛诊胃癌与非癌胃疾患的临床实用意义,近年来我们又采用改良Nixon氏法测定各种胃疾患者173例,正常人21例,共194例血清样本,以O·D(光密度)>0.36为Ehrlich呈色反应阳性,结果表明,胃癌组与非癌胃疾患组的阳性率的差别极为显著(P<0.01),而且,在各种胃炎疾患中,胃炎伴不典型增生和胃炎伴肠化生血清Ehrlich阳性反应明显增加,因此本法可作为临床筛诊胃癌和非癌胃疾患的参考。
We have reported that serum Ehrlich coloration can be used as a simple method for screening for cancerous tumors, and we found that the highest positive rate of gastric cancer was detected, which was 78.9%, to further evaluate the clinical application of this method in the diagnosis of gastric cancer and non-cancerous stomach diseases. Practical significance, in recent years we have adopted modified Nixon’s method to determine 173 cases of various stomach diseases, 21 cases of normal people, a total of 194 serum samples, O·D (optical density)> 0.36 for Ehrlich color reaction positive results It was shown that the difference in positive rate between gastric cancer group and non-cancerous gastric disease group was extremely significant (P<0.01). Moreover, in various gastritis diseases, the serum Ehrlich positive reaction of gastritis with dysplasia and gastritis with intestinal metaplasia was significantly increased. Therefore, this method can be used as a reference for clinical screening for gastric cancer and non-cancerous gastric diseases.