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目的:观察奥美拉唑联合阿莫西林、甲硝唑胶体果胶铋用于消化性溃疡治疗中的效果。方法:选择1990年1月至2015年6月诊治的消化性溃疡患者68例作为研究对象,随机分为治疗组和对照组各34例,治疗组采用奥美拉唑联合阿莫西林、甲硝唑、胶体果胶铋,对照组采用法莫替丁联合阿莫西林、甲硝唑,比较两组患者的治疗效果和不良反应情况。结果:治疗4周后,治疗组总有效率为97%,对照组总有效率为84.2%,治疗组有效率优于对照组,差异有统计学意义(P<0.05);治疗组中有2例出现恶心等不良反应,对照组共计有7例出现不良反应,治疗组用药安全性更高(P<0.05)。结论:奥美拉唑联合阿莫西林、甲硝唑、胶体果胶铋治疗消化性溃疡有着很好的临床效果,用药不良反应少,药物治疗安全性比较高,可以在临床治疗中应用。
Objective: To observe the effect of omeprazole combined with amoxicillin and metronidazole gel pectin bismuth in the treatment of peptic ulcer. Methods: Sixty-eight patients with peptic ulcer diagnosed and treated from January 1990 to June 2015 were randomly divided into treatment group (34 cases) and control group (34 cases). The treatment group was treated with omeprazole combined with amoxicillin, Azole and colloidal bismuth pectin. The control group was treated with famotidine combined with amoxicillin and metronidazole. The therapeutic effect and adverse reactions of the two groups were compared. Results: After 4 weeks of treatment, the total effective rate was 97% in the treatment group and 84.2% in the control group, and the effective rate in the treatment group was better than that in the control group (P <0.05). The treatment group had 2 Cases such as nausea and other adverse reactions, a total of 7 patients in the control group appeared adverse reactions, the treatment group medication safety (P <0.05). Conclusion: Omeprazole combined with amoxicillin, metronidazole and colloidal bismuth pectin has a good clinical effect in treating peptic ulcer with less adverse drug reactions and high safety of drug treatment, which can be used in clinical treatment.