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近10年来积累的在耳鼻咽喉肿瘤学中应用冷冻法的许多经验表明,该法疗效高,但易复发,Hancel氏等认为:其根本原因是冷冻坏死面积明显地小于致冷的肿瘤组织面积。A(?)等实验证明,肿瘤组织在超声波作用下,加以冷冻可达到明显地冷冻破坏。有鉴于此,乌克兰科学院物理研究所冷冻源物理实验室及基辅耳鼻咽喉研究所生物物理实验室合作于1979年设计了一套冷冻超声装置((?))。该装置是一直径10mm、弯成45°角的真空套管,工作部分长30mm。不仅可用于耳鼻咽喉器官表面,亦可在咽的各部位手术。冷冻探头靠强制循环的液氮工作,可使与组织接触的部分的温度迅速降至-170℃。
Many experiences accumulated in the otorhinolaryngology oncology in the past 10 years have shown that this method has a high curative effect, but is susceptible to recurrence. Hancel et al. believe that the fundamental reason is that the area of frozen necrosis is significantly smaller than the area of refrigerated tumor tissue. Experiments such as A(?) have proved that tumor tissue can freeze significantly under the action of ultrasonic waves to achieve freezing damage. In view of this, in 1979, a set of cryo-ultrasonic devices ((?)) was designed in collaboration with the Laboratory of Freezing Source Physics at the Institute of Physics, Ukrainian Academy of Sciences, and the Biophysical Laboratory at the Institute of Otolaryngology, Kiev. The device is a vacuum tube with a diameter of 10mm bent into a 45° angle and the working part is 30mm long. It can be used not only on the surface of otolaryngology organs, but also on all parts of the pharynx. Freezing the probe by forced circulation of liquid nitrogen allows the temperature of the part in contact with the tissue to quickly drop to -170°C.