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自1869年首次发现妊娠合并脾动脉瘤破裂,迄今共有99例报道。由于95%的病例在破裂前无任何症状,加之临床医师对该病的认识不足,孕产妇及围产儿的死亡率较高。因此,有必要对该疾病作一概括介绍。 1 流行病学 Stanley通过3600例血管造影发现一般人群中脾动脉瘤的发病率为0.78%。动脉瘤一般多见于男性,而女性脾动脉瘤的发病率是男性的4倍,经产妇的发病率比未产妇高,女性病人45%有过6次以上的妊娠。育龄妇女脾动脉瘤的发病率不详,妊娠合并用动脉瘤及其破裂的发生率不详。孕期脾动脉瘤极易发生破裂,25~40%的破裂发生在孕妇。文献所报道99例病人中,孕妇的死亡率为68.7%,胎儿为
It was the first time since 1869 that rupture of splenic aneurysm in pregnancy was found. So far, 99 cases have been reported. As 95% of cases without any symptoms before rupture, combined with clinicians lack of awareness of the disease, maternal and perinatal mortality is higher. Therefore, it is necessary to make a general introduction to the disease. Epidemiology Stanley found that the incidence of splenic aneurysms in the general population was 0.78% by 3600 angiograms. Aneurysms are more common in men, and the incidence of female splenic aneurysms is 4 times that of men, the incidence of maternal higher than non-mothers, 45% of female patients had more than 6 pregnancies. The incidence of splenic aneurysms in women of reproductive age is unknown, and the incidence of aneurysms and their ruptures during pregnancy is unknown. Splenic aneurysm during pregnancy prone to rupture, 25 to 40% of the rupture occurred in pregnant women. The 99 reported cases of the literature, the mortality rate of pregnant women was 68.7%, the fetus was