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目的阐述四川省1例脊髓灰质炎(脊灰)疫苗高变异株病例的流行病学调查与分析。方法按照相关要求,对疫情开展病例个案调查、实验室检测、病毒传播风险评估、应急处置等相关工作。结果 2014-06,四川省发现1例脊灰疫苗高变异株病例。事件发生后,四川省严格按照相关要求开展了多项应急处置措施,成功控制疫情,未再发现新发病例。结论通过本次事件的应对证明了《脊髓灰质炎野病毒输入性疫情和疫苗衍生病毒相关事件应急处置技术方案(试行)》的有效性和可操作性。同时,本次事件也暴露出了四川省在维持无脊灰工作中存在的一些漏洞和不足,需在今后的工作中不断完善和改进。
Objective To describe the epidemiological investigation and analysis of one case of poliovirus (poliovirus) highly variant in Sichuan province. Methods In accordance with the relevant requirements, the cases were investigated for cases of epidemics, laboratory tests, risk assessment of virus transmission, emergency response and other related work. Results In 2014-06, one case of poliovirus mutant was found in Sichuan Province. After the incident, Sichuan Province carried out a number of emergency measures in strict accordance with the relevant requirements and successfully controlled the epidemic. No new cases were found. Conclusions The response to this incident proves the effectiveness and operability of the “Technical Plan for Emergency Handling of Poliovirus Infectious Diseases and Vaccine-Derived Virus-Related Incidents (Trial)”. In the meantime, this incident also revealed some loopholes and deficiencies existing in Sichuan’s maintenance of polio-free work and needs to be continuously improved and improved in future work.