目的:本文旨在探讨Is期睾丸混合性生殖细胞瘤的不同治疗方法。方法:对2008年2月至2012年6月收治3例(年龄26~39岁)入院的Is期睾丸混合性生殖细胞瘤患者的临床资料进行回顾性分析和总结,并结合文献就该期肿瘤的临床特征进行探讨。结果:3例患者中1例只行根治性睾丸切除术,1例行根治性睾丸切除术+腹膜后淋巴结清扫术+BEP方案化疗,1例行根治性睾丸切除术+放疗。混合性生殖细胞瘤病理成分分别为左侧95%未成熟畸胎瘤、精原细胞瘤合并5%绒癌、胚胎性癌成分,左侧75%精原细胞瘤合并25%胚胎性癌、畸胎瘤成分,右侧90%成熟性畸胎瘤合并10%卵黄囊瘤。随访24个月3例患者肿瘤无局部复发和远处转移。结论:对于Is期睾丸混合性生殖细胞瘤诊断主要依靠体格检查、超声、MRI、血清肿瘤标记物测定等,确诊需要病理学检查,根治性睾丸切除术是其基础的治疗方法。 Aims: This article aims to explore the different treatment of Ischia mixed germ cell tumors. Methods: The clinical data of 3 patients (aged 26-39 years) admitted to Is orchid syncytial germ cell tumor from February 2008 to June 2012 were retrospectively analyzed and summarized. Combined with literature review, The clinical features of the discussion. Results: Of the three patients, only radical orchidectomy was performed in 1 case, radical orchiectomy + retroperitoneal lymph node dissection + BEP regimen and 1 case of orchidectomy + radiotherapy. The mixed germ cell tumor pathological components were left 95% immature teratoma, seminoma with 5% choriocarcinoma, embryonal carcinoma, 75% of the left seminoma with 25% of embryonal carcinoma, abnormal Tumor component, right 90% mature teratoma with 10% yolk sac tumor. All patients were followed up for 24 months without local recurrence and distant metastasis. Conclusion: The diagnosis of testicular germ cell germ cell tumor in Isis depends mainly on physical examination, ultrasound, MRI and serum tumor marker determination. Pathological examination is needed to confirm the diagnosis. Radical orchidectomy is the basic treatment method.