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目的:探讨应用CO2激光手术联合中药治疗小儿呼吸道乳头状瘤的疗效。方法:选取来本院手术治疗的年龄小于14岁的呼吸道乳头状瘤患者116例,并随机分为观察组和对照组。两组均采用CO2激光手术治疗,观察组在手术后同时给予中药治疗,观察两组患者中药治疗前后Derkay评分和手术间隔时间,并应用荧光定量PCR法检测中药治疗前后肿瘤组织中HPV6/11的含量。结果:观察组与对照组相比,手术间隔时间延长,Derkay评分降低,差异有统计学意义;观察组中药治疗前后HPV-DNA含量降低,差异有统计学意义,对照组无明显变化,差异无统计学意义。结论:CO2激光联合中药治疗小儿呼吸道乳头状瘤是一种有效的治疗方法。
Objective: To investigate the efficacy of CO2 laser surgery combined with traditional Chinese medicine in treatment of pediatric respiratory papilloma. Methods: A total of 116 patients with respiratory papilloma younger than 14 years old who underwent surgery in our hospital were randomly divided into observation group and control group. The two groups were treated with CO2 laser surgery. The observation group was treated with traditional Chinese medicine at the same time after surgery. The Derkay score and the operation interval before and after treatment were observed. The levels of HPV6 / 11 content. Results: Compared with the control group, the observation group had longer interval time and Derkay score, the difference was statistically significant. The content of HPV-DNA in the observation group before and after treatment decreased significantly, the difference was statistically significant, but there was no significant difference in the control group Statistical significance. Conclusion: CO2 laser combined with Chinese medicine treatment of pediatric respiratory papilloma is an effective treatment.