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目的 探讨耻骨上经膀胱前列腺切除术(suprapubic transvesical prostatectomy,TVP)与前列腺剜除术(modified transurethral resection,prostate,mTURP)对体积＞80mL前列腺增生(benign prostatic hyperplasia,BPH)患者手术相关指标变化情况的影响.方法 选取＞80mL老年BPH患者共80例,随机分为A组(40例)和B组(40例),分别采用TVP术式与mTURP术式治疗;比较两组疗效及安全性.结果 A组患者增生腺体组织切除量显著多于B组(P＜0.05);B组患者血红蛋白降低量、尿管留置时间、膀胱冲洗时间及住院时间均显著优于A组(P＜0.05);B组患者术后生活质量评分(QoL)和术后并发症发生率显著低于A组(P＜0.05).结论 前列腺剜除术式用于＞ 80mL老年BPH患者治疗临床疗效及安全性优于TVP术式.“,”Objective To investigate the influences of two kinds of prostatectomy such as TVP and mTURP on the operation related indexes of benign prostatic hyperplasia patients with volume larger than 80 mL.Methods Eighty elderly benign prostatic hyperplasia patients with volume larger than 80 ml were enrolled in the study and randomly divided into A group (40 patients with TVP operation) and B group (40 patients with mTURP operation);Operation time,hemoglobin loss amount,prostate tissue weight of resection,postoperative indwelling catheter time,postoperative bladder irrigation time,hospitalization time,the International Prostate Symptom Score (IPSS),prostate quality of life index score (QoL),maximal urinary flow rate (Qmax),bladder residual urine amount (PVR) before and after operation and the postoperative complications incidence of both groups were compared.Results The prostate tissue weight of resection in B group was significantly less than that in A group (P＜0.05).The moglobin loss amount,postoperative indwelling catheter time,postoperative bladder irrigation time,hospitalization time in B group were significantly better than those in A group (P＜0.05).The QoL scores after surgery and the incidence ofpostoperative complications of B group were significantly lower than that of A group (P＜0.05).Conclusion Compared with TVP operation,mTURP operation in the treatment of elderly patients with benign prostatic hyperplasia and volume larger than 80 ml possess the better clinical application value.