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目的了解江苏地区汉族人群血小板上CD36抗原表达的差异。方法应用流式细胞技术检测江苏地区140位汉族献血者血小板上CD36抗原的表达,并分析其表达量。结果本组江苏汉族献血者中,血小板上CD36抗原表达缺失型占比2.86%(4/140);非缺失型占比97.14%(136/140),其中低表达29例、中表达93例,高表达14例,三者的平均荧光强度(MFI)分别为1 821.4±21.8 vs 3 920.4±10.0 vs 8 787.4±63.7(P<0.05)。在CD36抗原表达的非缺失型中,男性127例、女性9例,其血小板上CD36抗原的MFI分别为3 678.36±13.5 vs 5 296.0±314.4。结论江苏地区汉族人群血小板CD36抗原表达具有多样性。
Objective To understand the difference of platelet CD36 antigen expression in Han nationality in Jiangsu province. Methods Flow cytometry was used to detect the expression of CD36 antigen on platelet of 140 Han donors in Jiangsu Province. Results Among the Han blood donors in Jiangsu province, the percentages of CD36 antigen-depleted platelets on platelets accounted for 2.86% (4/140), non-deletional forms accounted for 97.14% (136/140), of which 29 were low, 93 were middle- The mean fluorescence intensity (MFI) of the three were 1821.4 ± 21.8 vs 3320.4 ± 10.0 vs 7878.4 ± 63.7 (P <0.05), respectively. In the non-deletion type of CD36 antigen expression, there were 127 males and 9 females. The MFI of CD36 antigen on platelets was 3 678.36 ± 13.5 vs 5 296.0 ± 314.4 respectively. Conclusion The platelet CD36 antigen of the Han nationality in Jiangsu province is diverse.