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目的 探讨低钾性周期性麻痹合并多发性肌炎患者的发病机制、临床及病理特点。方法 分析观察二例患者的临床症状、血钾、血清酶、心电图的变化 ,并行肌电图、肌肉活检。结果 患者血钾降低、血清酶升高、心电图呈低钾改变 ,肌电图示类肌源性改变 ,肌活检示炎性改变。经补钾等治疗 ,症状缓解。结论 对持续时间较长的低钾性周期性麻痹患者 ,应行血清酶、肌电图、肌肉活检 ,明确有无其它肌病存在的可能 ,以便及时诊治。
Objective To investigate the pathogenesis, clinical and pathological features of patients with hypokalemic periodic paralysis complicated with polymyositis. Methods The clinical symptoms, serum potassium, serum enzymes and electrocardiogram were observed and analyzed in two cases. Parallel electromyography and muscle biopsy were performed. Results Patients with lower serum potassium, elevated serum enzymes, ECG showed hypokalemia, EMG showed myogenic changes, muscle biopsy showed inflammatory changes. After treatment such as potassium, symptoms relieved. Conclusion Patients with longer duration of hypokalemic periodic paralysis should be serum enzyme, EMG, muscle biopsy, clear the existence of other myopathies may exist for timely diagnosis and treatment.