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临床对于患先天愚型胎儿的高危组孕妇,尤其是年龄≥35岁者,常用羊水穿刺以作诊断。据作者所知,迄今尚未见到有超声波鉴别正常与先天愚型胎儿的报道,作者描述了一种超声波征象可提示患先天愚型的高度危险性,并需要作进一步的检查。作者在一年半内曾为15～18孕周的胎儿作了904例羊水穿刺与细胞遗传学检查,同时应用超声波进行细致的胎儿解剖结构观察,发现3例颈枕后部有过多的软组织积聚与皮肤增厚,此种异常可与水囊瘤相鉴别,因为后者是沿胎儿颈部生长的囊性肿瘤,而作者的3例颈枕后部增厚呈扁平状,且二侧对称,并非膨隆状与囊性。本组羊水穿刺904例经核
Clinical For those with high risk of Down’s syndrome, pregnant women, especially those aged> 35 years old, amniocentesis for diagnosis. To the best of the author’s knowledge, so far there have been no reports of sonographically normal and Down’s syndrome-type fetuses. The authors described an ultrasound sign that could indicate a high risk of Down’s syndrome and required further examination. In a year and a half, the author made 904 cases of amniocentesis and cytogenetics for fetuses aged from 15 to 18 weeks. Ultrasound was used to observe the anatomy of the fetus. Three cases of excessive soft tissue behind the neck pillow were found Accumulation and skin thickening, such abnormalities can be differentiated from the hydrosarcoma, because the latter is a cystic tumor that grows along the fetal neck, while the authors of 3 cases of the back of the neck pillow thickening was flat, and bilateral symmetry , Not bulky and cystic. Amniocentesis in this group of 904 cases of nuclear