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目的:观察薏苡仁油对小鼠的抗炎消肿作用。方法:用鸡蛋清致小鼠足跖肿胀模型、二甲苯致小鼠耳廓肿胀模型、醋酸所致小鼠腹腔毛细血管通透性升高模型,分别考察薏苡仁油对小鼠的抗炎消肿作用。结果:与对照组比较,薏苡仁油能明显抑制蛋清和二甲苯所致的小鼠的炎症反应,并降低醋酸所致的小鼠腹腔毛细血管通透性(P<0.05或P<0.01)。结论:薏苡仁油有一定抗炎消肿作用,该作用可能与降低毛细血管通透性有关。
Objective: To observe the effect of Coix Seed Oil on anti-inflammatory and swelling in mice. Methods: Egg-induced mouse paw edema model, xylene-induced auricle edema model and acetic acid-induced mouse models of peritoneal capillary permeability were used to investigate the anti-inflammatory effects of Coix seed oil on mice Swollen effect. Results: Compared with the control group, Coix seed oil could significantly inhibit the inflammation of mice induced by albumen and xylene and reduce the peritoneal capillary permeability of mice induced by acetic acid (P <0.05 or P <0.01). Conclusion: Coix seed oil has a certain anti-inflammatory swelling, the role may be related to reducing capillary permeability.