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腮腺未分化癌是一种由分化极差的细胞所组成的恶性上皮性肿瘤。作者从1950年~1980年间于日本千叶大学医学院耳喉科和千叶县Asahi 医院共检查到腮腺原发性肿瘤555例(非上皮性肿瘤除外),恶性肿瘤为176例。其中有18例诊断为未分化癌,占总数的3.2%,占恶性肿瘤的10.2%.作者根据细胞的大小把未分化癌分为小细胞型和大细胞型两种类型.小细胞型(12/18;66.7%)。癌细胞呈园形或卵圆形,与淋巴细胞体积相等或稍大,无胞浆.核染色质较丰富,有一、二个核仁,核分裂象多见.癌巢内形成少数微假性腺管,癌巢周围
Parotid undifferentiated carcinoma is a malignant epithelial tumor composed of very poorly differentiated cells. The authors examined 555 cases of primary tumors of the parotid gland (except for non-epithelial neoplasia) from 1950 to 1980 at the Department of Otolaryngology, Chiba University School of Medicine, Japan, and Asahi Hospital, Chiba Prefecture. The number of malignant tumors was 176 cases. Among them, 18 cases were diagnosed as undifferentiated carcinoma, which accounted for 3.2% of the total and accounted for 10.2% of malignant tumors. The authors divided undifferentiated carcinoma into two types: small cell type and large cell type according to the size of cells. /18; 66.7%). The cancer cells are round or oval, equal to or slightly larger than the lymphocytes, and have no cytoplasm. The nuclear chromatin is rich, with one or two nucleoli, and mitoses are more common. A small number of microscopic ducts are formed in the cancer nest. , around the cancer nest