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以前认为,糖尿病所特有的全部代谢过程是由于胰岛素不足、组织中葡萄糖转化及其利用减弱所引起。但早在1930年就实验证明,仅在保留垂体及肾上腺时胰岛素不足才引起糖尿病。而它们被切除后糖尿病的发生减轻。动物切除垂体及肾上腺后长期注射大剂量垂体提液或糖皮质激素引起糖尿病。这些资料使糖尿病的发生是由于胰岛素绝对和相对不足的胰腺观点得到补充。这个理论被一系列研究所证实,如长时间注射大剂量的
It was previously thought that all of the metabolic processes that are characteristic of diabetes are caused by inadequate insulin, impaired glucose turnover and its utilization in the tissues. But as early as 1930 experiments show that, only in the retention of the pituitary and adrenal insufficiency caused by diabetes. And they are cut off to reduce the incidence of diabetes. Long-term high-dose injection of pituitary or glucocorticoid caused by long-term injection of pituitary and adrenal to cause diabetes. These data make the occurrence of diabetes due to the absolute and relative insufficiency of insulin in the pancreas. This theory is confirmed by a series of studies, such as long-term injection of large doses