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目的:探讨小梁切除术中应用羊膜移植治疗难治性青光眼的临床疗效。方法:将临床收治的20例(20眼)难治性青光眼患者施行小梁切除术联合巩膜瓣下生物羊膜植入术,术后观察其视力、前房、滤过泡和眼压等情况。结果:术后眼压明显降低,视力稳定或提高,功能性滤过泡形成良好,并发症仅为早期浅前房和低眼压。结论:羊膜移植应用于难治性青光眼小梁切除术可有效地防止滤过泡的瘢痕组织形成,并发症少,是治疗难治性青光眼安全、有效的手术方法。
Objective: To investigate the clinical effect of amniotic membrane transplantation for refractory glaucoma in trabeculectomy. Methods: Twenty patients (20 eyes) refractory glaucoma admitted to our hospital were treated with trabeculectomy combined with amniotic membrane implantation under scleral flap. Visual acuity, anterior chamber, filtration bleb and intraocular pressure were observed after operation. Results: Postoperative intraocular pressure was significantly lower, visual acuity was stable or improved, functional filtration bleb formation is good, complications are only early shallow anterior chamber and hypotensive pressure. CONCLUSION: Amniotic membrane transplantation in refractory glaucoma trabeculoplasty can effectively prevent scar formation of bleb and has fewer complications. It is safe and effective for the treatment of refractory glaucoma.