沙眼衣原体 (chlamydia trachom atis CT)是一种常见的性传播疾病病原体 ,我国人群中 CT感染率呈上升的趋势 ,可引起前庭大腺炎、宫颈炎、输卵管炎、盆腔炎、异位妊娠、不育等多种疾病。孕妇感染 CT通过宫内感染等方式 ,直接损害发育中的胎儿 ,导致自然流产、早产、胎膜早破、死产、死胎等严重后果。CT感染的细胞表面有 CT抗原存在 ,可诱导机体自身免疫反应 ,造成损害 ;子宫内膜细胞、蜕膜细胞或胎儿滋养层细胞急性或持续性 CT感染 ,可根本性的改变母胎的耐受机制 ,造成妊娠的失败。CT主要通过性交传播 ,母婴间可通过宫内感染、产道感染、产褥期感染等方式垂直传播 CT。 CT的诊断主要依赖实验室检查。 CT的治疗首选四环素类药物、大环内酯类为次选药物、再选喹诺酮类药物、绝大多数的青霉素类药物对 CT无效 ,一般不应使用 ,但可用羟氨苄青霉素治疗。妊娠期感染 CT的孕妇 ,可给予红霉素或阿莫西林治疗 ,不能用四环素类药物和喹诺酮类药物 Chlamydia trachoma atis CT is a common pathogen of sexually transmitted diseases, the trend of CT infection in our population is on the rise, can cause bartholinitis, cervicitis, salpingitis, pelvic inflammatory disease, ectopic pregnancy, not Education and other diseases. Pregnant women infected with CT through intrauterine infection, etc., directly damage the developing fetus, leading to spontaneous abortion, premature birth, premature rupture of membranes, stillbirth and stillbirth and other serious consequences. CT-infected cells in the presence of CT antigens can induce the body’s own immune response, causing damage; endometrial cells, decidual cells or fetal trophoblast cells acute or persistent CT infection can fundamentally change the mother’s tolerance mechanism , Resulting in the failure of pregnancy. CT is mainly transmitted through intercourse, maternal and child can be transmitted through the intrauterine infection, birth canal infection, puerperal infection and other means of vertical transmission of CT. The diagnosis of CT depends mainly on laboratory tests. CT treatment preferred tetracycline drugs, macrolides as the second choice drug, and then quinolone drugs, the vast majority of penicillin drugs on CT invalid, generally should not be used, but can be treated with amoxicillin. Pregnant women infected with CT during pregnancy can be given erythromycin or amoxicillin treatment, can not be used tetracyclines and quinolones