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血管平滑肌细胞(VSMC)的增殖和迁移引起内膜增生肥厚是导致经皮腔内冠状动脉成形术(PTCA)后再狭窄的关键因素之一,也是动脉粥样硬化(AS)斑块形成的一个主要病理基础[1]。观察表明,患者在行PTCA后3~6个月有30%~50%的再狭窄率,然而迄今尚无有效的药物治疗。过氧化物酶体增生物激
Proliferation and migration of vascular smooth muscle cells (VSMCs) causing intimal hyperplasia is one of the key factors leading to restenosis after percutaneous transluminal coronary angioplasty (PTCA) and is also a form of atherosclerotic plaque formation The main pathological basis [1]. Observations have shown that patients with PTCA after 3 to 6 months 30% to 50% restenosis rate, but so far there is no effective drug treatment. Peroxisome proliferators