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溶出度快、中、慢的三种氨茶碱片的兔体内试验表明:其TM间无显著性差异,(P>0.05),CM间和AUC间均有显著性差异(P<0.05);其体外溶出度与CM和AUC间有极显著相关性(P<0.01)。
The in vivo tests of three aminophylline tablets showed that there was no significant difference between the TM groups (P> 0.05), and there was a significant difference between the CM and the AUC (P <0.05). In vitro dissolution and CM and AUC have a very significant correlation (P <0.01).