论文部分内容阅读
1 引 言麻醉是药物与机体之间相互作用的一个复杂动态过程。麻醉药物作用于机体可对肾血流量、肾小球滤过率、肾小球旁器、肾小管及肾自主调节功能产生影响。麻醉药一般有较高的油、水分布系数,能从肺迅速消除,部分经肝生物转化,生成水溶性增高的代谢物从肾排泄。对肾功能的
1 Introduction Anesthesia is a complex and dynamic process of drug-body interaction. Anesthetic drugs on the body can affect renal blood flow, glomerular filtration rate, glomerular bypass, renal tubular and renal autonomic modulation. Anesthetic drugs generally have a high oil and water distribution coefficient, which can be rapidly eliminated from the lungs and partly transformed by the liver to generate metabolites that increase in water solubility and excreted from the kidneys. Right kidney function