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程×,女,41岁,南宁市无线电三厂工人,湖北籍。因腹痛腹泻服药后突发性心慌胸闷,头晕眼花,皮肤痒,继而不省人事10分钟,于1988年5月16晚11时30分入院。患者因下腹痛半天,腹泻6次,水样便,于当天上午到地段医院看病,拟“急性肠炎”取回中药三剂(茯苓、山楂、陈皮、霍香、生姜、神曲、甘草)外加山东新华制药厂生产的吡哌酸(简称PPA,下同)250mg共12片。上、中、下午三次煎服中药腹痛好转,腹泻减轻,无不良反应。晚上10点50分开始服用PPA 2片,服后15分钟即见腹部不适,心慌、胸闷、全身皮肤骚痒,头昏眼花,续而昏迷,不省人事.家属即用手按压其人中穴,急送本院抢救。既往曾有一次青霉素过敏史。体检:T36℃,R26次/分,BP10.7/7.3kPa,脉搏
Cheng ×, female, 41 years old, three workers in Nanning Radio Factory, Hubei nationality. Due to abdominal pain after diarrhea sudden onset of panic chest tightness, dizziness, itchy skin, then unconscious for 10 minutes, at 11:30 on May 16, 1988 admission. Patients due to lower abdominal pain for a long time, diarrhea 6 times, watery stool, in the morning to the site of the hospital, to be “acute enteritis” to retrieve three Chinese medicine (Poria, hawthorn, dried tangerine peel, Huoxiang, ginger, Divine Comedy, licorice) Piperazine hydrochloride produced by the pharmaceutical factory (referred to as PPA, the same below) 250mg a total of 12 tablets. On the middle and afternoon three decoction Chinese medicine abdominal pain improved, reduce diarrhea, no adverse reactions. PPA 2 at 10: 50 pm, after serving 15 minutes to see the abdominal discomfort, palpitation, chest tightness, systemic skin itching, dizziness, and coma unconsciousness, unconsciousness. , Rush to our hospital for rescue. Previously had a history of penicillin allergy. Physical examination: T36 ℃, R26 beats / min, BP10.7 / 7.3kPa, pulse