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为探讨乙型肝炎病毒(HBV)携带者血清中 HBeAg 含量及其亚分的临床意义,本文应用单克隆酶联免疫吸附测定法(ELISA)测定血清中 HBeAg 含量,应用硫酸铵盐析法及聚丙烯酰胺凝胶电泳法(PAGE)测定 HBeAg 的亚分(A 和 B)。调查了19.3(男121,女72)例 HBV 携带者,年龄6～66(平均37.5)岁,其中无症状 HBsAg 携带者(ASC)65例,慢性持续性肝炎(CPH)43例,慢性活动性肝炎(CAH)54例,肝硬化(LC)31例。结果①193例中有69例(其中男43例)检出 HBe
In order to investigate the clinical significance of HBeAg in serum of HBsAg carriers and its sub-clinical significance, HBeAg in serum was determined by monoclonal enzyme-linked immunosorbent assay (ELISA) The sub-fractions of HBeAg (A and B) were determined by acrylamide gel electrophoresis (PAGE). A total of 19.3 (121 male and 72 female) HBV carriers aged 6 to 66 (mean 37.5 years) were investigated. Among them, 65 were asymptomatic HBsAg carriers (ASC), 43 were chronic persistent hepatitis (CPH), and chronic active 54 cases of hepatitis (CAH), 31 cases of liver cirrhosis (LC). Results ① In 193 cases, 69 cases (including 43 males) detected HBe