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应用ＲＴ－ＰＣＲ方法，以β２微球蛋白（β２Ｍ）为内标，建立了人白细胞钙调素ｍＲＮＡ表达水平的半定量测定方法。初步了解了不同时期内服用钙拮抗剂（ＣａＡ）的心血管病患者细胞内ＣａＭｍＲＮＡ表达的变化规律，从而为临床疾病的防治提供了一定的依据
Using RT-PCR method and β2 microglobulin (β2M) as an internal standard, a semi-quantitative determination method of human leukocyte calmodulin mRNA expression was established. To understand the changes of intracellular CaM mRNA expression in patients with cardiovascular disease taking calcium antagonists (CaA) in different periods, and to provide a basis for the prevention and treatment of clinical diseases