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目的探讨硫辛酸治疗糖尿病周围神经病变的疗效观察。方法 2009年2月至2011年2月收治的糖尿病周围神经病变200例,分为a-硫辛酸组100例,甲钴铵100例,观察两组临床疗效。结果 a-硫辛酸组总有效率94.00%明显优于甲钴铵组总有效率72.00%,两组总有效率比较,差异有统计学意义(P<0.05)。结论通过对两组病例进行观察,a-硫辛酸组总有效率94.00%明显优于甲钴铵组总有效率72.00%,在糖尿病周围神经病变a-硫辛酸能够清除多种自由基有效保护各种细胞,保护血管内皮,改善神经传导速度,临床疗效确切,是治疗糖尿病周围神经病变首选治疗方案。
Objective To investigate the efficacy of lipoic acid in the treatment of diabetic peripheral neuropathy. Methods 200 patients with diabetic peripheral neuropathy admitted from February 2009 to February 2011 were divided into a-lipoic acid group (n = 100) and methylcobalamin (n = 100). The clinical curative effect was observed. Results The total effective rate of a-lipoic acid group was 94.00%, which was significantly better than that of mecobalamin group. The total effective rate was 72.00%. The total effective rate was statistically significant (P <0.05). Conclusions The two groups of patients were observed, a-lipoic acid group, the total effective rate 94.00% was significantly superior to the total effective rate of methycobalamin group 72.00%, in diabetic peripheral neuropathy a-lipoic acid can clear a variety of free radical protection Seed cells, vascular endothelial protection, improve nerve conduction velocity, the exact clinical efficacy, is the treatment of diabetic peripheral neuropathy treatment of choice.