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通过大鼠肾缺血再灌注损伤模型研究芦丁对肾脏缺血再灌注损伤的保护作用及其机制。结果发现，芦丁通过清除氧自由基，保护缺血再灌注损伤的肾脏功能，保护作用的机制可能与降低组织内Fe2+水平，抑制OH产生及直接清除自由基有关。
To study the protective effect and its mechanism of rutin on renal ischemia-reperfusion injury in rat models of renal ischemia-reperfusion injury. It was found that rutin protects renal function of ischemia-reperfusion injury by scavenging oxygen free radicals, and the protective mechanism may be related to the reduction of Fe2+ levels in tissues, the inhibition of OH production, and the direct scavenging of free radicals.