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目的:观察中西医结合治疗原发性高血压的临床效果。方法:入选患者随机分为治疗组(50例)和对照组(50例),对照组服用依那普利5 mg,每日2次,硝苯地平缓释片10 mg,每日2次;治疗组在对照组基础上自拟清脑降压饮治疗每日1剂,早晚分服;治疗4周为1个疗程,1个疗程后统计疗效;观察两组治疗前后的血压变化、综合疗效、血流学改变、不良反应等情况。结果:治疗组临床总有效率为96%,明显优于对照组的84%(P<0.05);两组治疗后收缩压、舒张压、全血黏度(高切和低切)、血浆黏度和纤维蛋白原均比治疗前下降(P<0.01或P<0.05),且2组治疗后比较,治疗组各项指标下降更为明显(P<0.05)。结论:调络降压饮结合西医在改善高血压症状及血液流变学等方面效果显著。
Objective: To observe the clinical effect of integrated traditional Chinese and western medicine on essential hypertension. Methods: The patients were randomly divided into treatment group (n = 50) and control group (n = 50). The control group received enalapril 5 mg twice daily and nifedipine 10 mg twice daily. The treatment group on the basis of the control group self-prepared Qingnaojiangyin Decoction daily treatment 1, morning and evening; 4 weeks for a course of treatment, a course of treatment after the statistical effect; observed two groups before and after treatment of blood pressure changes, the comprehensive effect , Changes in blood flow, adverse reactions and so on. Results: The total effective rate of the treatment group was 96%, which was significantly better than that of the control group (P <0.05). The systolic blood pressure, diastolic blood pressure, whole blood viscosity (high and low cut), plasma viscosity Fibrinogen decreased compared with that before treatment (P <0.01 or P <0.05). After treatment, the indexes in treatment group decreased more obviously (P <0.05). Conclusion: Tiaojiao hypotensive combined with Western medicine in improving the symptoms of hypertension and hemorheology significantly.