患呼吸窘迫综合征(RDS)的新生儿在监护病房进行机械通气往往因躁动等原因容易发生气胸、颅内出血等并发症,故需用镇静药。作者试用咪达唑仑(mida- zolam)对此类患儿进行前瞻性、随机双盲研究,并以安慰剂作对照。监测血流动力学(心率、收缩压、舒张压)及五项行为评分评估镇静程序,并纪录各种并发症和用药后的副作用。作者选择46名患RDS进行机械通气 Neonates with respiratory distress syndrome (RDS) are often sedated with sedatives because mechanical ventilation in the intensive care unit tends to develop complications such as pneumothorax and intracranial hemorrhage due to restlessness and other causes. The authors trial midazolam (midazolam) prospective, randomized double-blind study of these children, and placebo for the control. Hemodynamics (heart rate, systolic blood pressure, diastolic blood pressure) and five behavioral scores were monitored for sedation, and various complications and side effects after treatment were recorded. The authors selected 46 patients with RDS for mechanical ventilation