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【目的】研究中国沿海及内陆两种不同膳食模式对初乳及婴儿脐血血浆磷脂脂肪酸的影响。【方法】收集沿海温州及内陆常州两地配对5 d母初乳及脐血20例及82例进行观察性对照研究,采用高效毛细气相色谱分析技术检测初乳及婴儿脐血血浆中磷脂脂肪酸浓度。【结果】温州组5 d母初乳的脂肪酸中二十二碳六烯酸(docosa-hexaenoic acid,DHA)和二十碳五烯酸(docosapentaenoic acid,EPA)含量高于常州组,而常州组亚油酸(linolenic acid,LA)和α-亚麻酸(-lαinolenic acid,ALA)高于温州组;常州组婴儿脐血中血浆磷脂脂肪酸中LA和ALA高于温州组,而温州组中EPA高于常州组。【结论】两地5 d母初乳及脐血血浆磷脂脂肪酸中脂肪酸的差异,反映了其与母亲长期膳食结构的相关性。
【Objective】 The objective of this study was to investigate the effect of two different dietary patterns in coastal and inland China on plasma phospholipid fatty acids in colostrum and infant cord blood. 【Method】 The control collaterals and umbilical cord blood of 5 d maternal and umbilical cord blood were collected from Wenzhou and inland areas of Changzhou. Observational control study was carried out. High-performance capillary GC analysis was used to detect the content of phospholipid fatty acids concentration. 【Result】 The content of docosa-hexaenoic acid (DHA) and docosapentaenoic acid (EPA) in the fatty acids of Wenzhou colostrum at 5 d was higher than that of Changzhou group, while that of Changzhou group Linolenic acid (LA) and α-linolenic acid (ALA) were higher in Wenzhou group than those in Wenzhou group. LA and ALA in plasma phospholipid fatty acid in cord blood of Changzhou group were higher than those in Wenzhou group, In Changzhou group. 【Conclusion】 The differences of fatty acids in plasma phospholipid fatty acids of 5 d mother and umbilical blood of both places reflect the correlation between them and the long-term dietary structure of mothers.