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Calder报道菸酸有改善离体兔心自发部份传导阻滞的作用。我们在实验中也曾观察到菸酰胺对实验性心律失常有防治效能。本文研究菸酰胺对实验性心脏传导阻滞的影响。实验方法实验用体重1.5~2.0公斤家兔及450~600克豚鼠。击毙后,取出心脏,用改良兰氏法以洛氏液灌流离体心脏,并将悬挂的心脏置于盛有38~39℃生理盐水的容器内,记录离体心
Calder reports that nicotinic acid improves the spontaneous partial conduction block in isolated rabbit hearts. We have also observed in experiments that nicotinamide has anticonvulsant effects on experimental arrhythmias. This article studies the effects of niacinamide on experimental heart block. Experimental methods Experimental weight 1.5 ~ 2.0 kg rabbits and 450 to 600 grams of guinea pigs. After being killed, the heart was removed, the isolated heart was perfused with Rockwell’s method using a modified Rankine method, and the suspended heart was placed in a container containing physiological saline at 38-39 ° C., and the isolated heart