This study was to investigate the effects of aqueous decotion from three Chinese medicinal herb additives( Cyrtomium fortunei,prescription I and prescription II) on non-specific immunity of 1 + age old Amur sturgeon( Acipenser schrencki Brandt) by oral perfusion. Cyrtomium fortunei,prescription I and prescription II were orally given to 15 fishes for each experimental group once a day,with the concentration of 9,175 and 36 g /50 kg body weight,respectively. The administration was lasted for 14 days. Meanwhile,distilled water was orally given as the control. After the experiment,some of the experimental fishes were stimulated with high temperature( 30 ℃) for two hours. Sampling was performed from fishes treated at 22 ℃ and 30 ℃ for measuring the protein content in the serum,phagocytic activity of leucocytes and the activity of the lysozyme in six tissues. The results indicated that Cyrtomium fortunei and prescription II could help to enhance the content of various proteins and the phagocytic activity of leucocytes. There was no significant change in the effects between these two additives at either the normal temperature or high temperature. Prescription I did not show an obvious effect on the immunity of fishes at the normal temperature,but it did in promoting high-efficiency response and improving immunoregulation of fish shocked by some stimuli. This study was to investigate the effects of aqueous decotion from three Chinese medicinal herb additives (Cyrtomium fortunei, prescription I and prescription II) on non-specific immunity of 1 + age old Amur sturgeon (Acipenser schrencki Brandt) by oral perfusion. Cyrtomium fortunei, prescription I and prescription II were orally given to 15 fishes for each experimental group once a day, with the concentration of 9,175 and 36 g / 50 kg body weight, respectively. The administration was lasted for 14 days. as the control. some of the experimental fishes were stimulated with high temperature (30 ° C) for two hours. Sampling was performed from fishes treated at 22 ° C and 30 ° C for measuring the protein content in the serum, phagocytic activity of leucocytes and the activity of the lysozyme in six tissues. The results indicated that Cyrtomium fortunei and prescription II could help to enhance the content of various proteins and the There was no significant change in the effects between these two doses at either the normal temperature or high temperature. There was no significant change in the effects between these two doses either at the normal temperature or high temperature. -efficiency response and improving immunoregulation of fish shocked by some stimuli.