A series of PtCuCeMgAl quintuple hydrotalcite-like compounds with different Ce contents were synthesized by one-pot method.After calcining and reduction,CeO2-modified Mg(Al)O-supported Pt-Cu alloy catalysts were obtained.To understand the effect of Cu and Ce,the structure and physico-chemistry properties of the catalysts were characterized and analyzed,and the catalytic behaviors were investigated in a direct dehydrogenation of propane to propene.The results show that the Pt4+,Cu-2+,and Ce3+ ions can be incorporated into the brucite-like layers and the Ce content significantly affects the interaction strength between Pt and Cu and the dehydrogenation performance of propane.Under the reaction conditions,the highest propane conversion (45％) with 89％ selectivity to propene and a 40％ propene yield were achieved with a 0.3 wt％ Ce-modified PtCu/Mg(Al)O catalyst.The improved catalytic performance is related to the easy formation of Pt-Cu alloy phase,excellent resistance to sintering,and coke deposits of active components modified by CeO2.