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从1992年冬至1993年春对妊娠晚期孕妇体内的维生素D(VitD)状况进行了研究。31例孕妇于妊娠32周时取血标本后随机分为两组:补充VitD组(16例),和未补充VitD组(15例)。分娩时第二次取母亲血,并收集脐血及新生儿血。设12例同龄健康未孕妇女为对照组。测血清25—羟胆骨化醇〔25(OH)D_3〕、钙(Ca)、磷(P)、碱性磷酸酶(AKP)、甲状旁腺素(PTH)及降钙素(CT)。结果显示:(1)正常孕妇血25(OH)D_3水平随孕期而下降,尤以后期为著。(2)补充组孕妇分娩时25(OH)D_3水平较32周时升高,其母血、脐血及新生儿血25(OH)D_3水平均高于未补充组,但母血PTH、CT、Ca、P等调节系统无明显变化;(3)两组孕妇分娩
From the winter of 1992 to the spring of 1993, the status of vitamin D in pregnant women in the third trimester of pregnancy was studied. Thirty-one pregnant women were randomly divided into two groups at the 32th week of pregnancy: VitD group (16 cases) and VitD group (15 cases). The second time to take maternal blood at delivery, and collect cord blood and neonatal blood. Set 12 cases of healthy pregnant women with the same age as the control group. Serum 25-hydroxycholecalciferol [25 (OH) D_3], calcium (Ca), phosphorus (P), alkaline phosphatase (AKP), parathyroid hormone (PTH) and calcitonin (CT) were measured. The results showed that: (1) The normal pregnant women blood 25 (OH) D_3 levels decreased with pregnancy, especially in late. (2) The level of 25 (OH) D_3 in pregnant women in the supplementary group was higher than that in the 32nd week. The levels of 25 (OH) D_3 in maternal blood, cord blood and neonates were higher than those in the non-supplement group. , P and other regulatory system no significant change; (3) two groups of pregnant women childbirth