新生儿缺氧缺血性脑病(HIE)是由于缺氧引起的脑细胞病理生理改变。脑水肿在其中起着重要作用。因此,及时有效的控制脑水肿是治疗HIE,减少死亡率和致残率的关键。临床已常规使用甘露醇、地塞米松脱水治疗,但方法各异。地塞米松糖皮质激素的使用还存在一些不同看法。我们对1995～1996年共收治50例HIE脑水肿患儿进行了回顾分析,现报告如下。 Neonatal hypoxic-ischemic encephalopathy (HIE) is due to hypoxia-induced changes in the pathophysiology of brain cells. Brain edema plays an important role. Therefore, the timely and effective control of brain edema is the key to the treatment of HIE, reduce mortality and morbidity. Clinical routine use of mannitol, dexamethasone dehydration, but different ways. Dexamethasone glucocorticoid use there are still some different views. We retrospectively analyzed 50 children with HIE cerebral edema from 1995 to 1996, and the report is as follows.