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本文用ELISA法检测50例IDDM患者的抗ss-DNA(IgG)、ds-DNA(IgG)和ACL(IgM、IgG)抗体,阳性率分别为18％、8％、26％和20％,明显高于对照组。用免疫荧光法检测27例IDDM患者ICA和ANA抗体,阳性率分别为29.5％和25.9％,高于正常对照5.0％和0。ICA(+)、(-)两组的SS-DNA、ds-DNA、ACL抗体阳性间无明显差异(P>0.05)。近期发病的IDDM患者ICA、ds-DNA及ANA明显高于发病较久的患者,而SS-DNA和ACL(IgG和IgM)两组间无差别。上感史对各自身抗体无明显影响(P>0.05)。
The anti-ss-DNA (IgG), ds-DNA (IgG) and anti-ACL (IgM, IgG) antibodies in 50 patients with IDDM were detected by ELISA in 18%, 8%, 26% and 20% Higher than the control group. The positive rates of ICA and ANA in 27 IDDM patients by immunofluorescence were 29.5% and 25.9% respectively, which were higher than 5.0% and 0 of normal controls. There was no significant difference between the ICA (+) and (-) SS-DNA, ds-DNA and ACL antibody positive groups (P> 0.05). The recent incidence of IDDM patients with ICA, ds-DNA and ANA was significantly higher than the incidence of patients, and SS-DNA and ACL (IgG and IgM) no difference between the two groups. On the history of the flu on each antibody had no significant effect (P> 0.05).