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目的观察潜阳封髓丹对肾阳不足型恶性肿瘤患者化疗相关性口腔黏膜炎的疗效。方法将96例肾阳不足型化疗相关性口腔黏膜炎的患者随机分为潜阳封髓丹组和康复新液组各48例,潜阳封髓丹组用潜阳封髓丹水煎漱口及含服,康复新液组用康复新液漱口及含服,2组疗程均为14天。比较2组间KPS评分、平均溃疡期和疼痛评分的差异。结果潜阳封髓丹组治疗后KPS评分较康复新液组提高,平均溃疡期较康复新液组缩短,疼痛评分较康复新液组减小,组间比较差异均有统计学意义(P<0.05)。结论潜阳封髓丹漱口及含服对肾阳不足型恶性肿瘤化疗相关性口腔黏膜炎有较好疗效。
Objective To observe the curative effect of Qiangyang Fengdansand on chemotherapy-associated oral mucositis in patients with kidney-yang insufficiency. Methods Ninety-six patients with kidney-yang-deficiency-type chemotherapy-associated oral mucositis were randomly divided into four groups: 48 cases in each group. Each group included 48 cases in each group, And with clothing, rehabilitation of new liquid group with rehabilitation of new mouthwash and clothing, two groups of treatment were 14 days. The differences of KPS score, average ulcer period and pain score between two groups were compared. Results After treatment, the KPS score in Qianyang Capsule group was significantly higher than that in KFF group, the average ulcer period was shorter than that in KFF group, and the pain score was lower than that in KFF group. There was significant difference between the two groups (P < 0.05). Conclusions The latent Yang closure cord marrow mouthwash and containing service on the kidney-yang deficiency type of malignant tumor chemotherapy-related oral mucositis have a good effect.