细胞色素P450（CYP）是生物体内由血红蛋白组成的一个特大氧化酶家族。近年来，越来越多的资料表明，CYP2C亚族中的CYP2C9已成为人体最重要的药物代谢酶之一。CYP2C9是人体CYP2C亚族中4个已知成员之一，其他3个为CYP2C8，CYP2C18和CYP2C19。它们的氨基酸序列820以上一致，序列 Cytochrome P450 (CYP) is a family of large oxidases composed of hemoglobin in the body. In recent years, more and more data indicate that CYP2C9 in the CYP2C subfamily has become one of the most important drug metabolizing enzymes in the human body. CYP2C9 is one of four known members of the human CYP2C subfamily and the other three are CYP2C8, CYP2C18 and CYP2C19. Their amino acid sequence is more than 820, the sequence