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目的：研究低血容量性休克和复苏后胃肠粘膜内ｐＨ值（ｐＨｉ）的变化规律，为指导隐性代偿性休克复苏提供理论依据。方法：雄性山羊６只，用Ｗｉｇｇｅｒｓ法造成失血后低血容量性休克〔平均动脉压６．０ｋＰａ（１ｋＰａ＝７．５ｍｍＨｇ）维持１小时〕，快速回输失血和２倍的林格氏液，在胃和回肠处造口，分别置入胃和肠粘膜张力计，动态监测胃肠粘膜ｐＨｉ。结果：（１）胃肠粘膜ｐＨｉ随休克程度加重而进行性降低，复苏后４８小时恢复至伤前水平；（２）胃肠粘膜ｐＨｉ变化与门静脉血流量和其ｐＨ变化呈显著正相关，与门静脉血乳酸和二胺氧化酶含量呈显著负相关。结论：胃肠粘膜ｐＨｉ能反映胃肠粘膜缺血和酸中毒状态，是指导隐性代偿性休克复苏的敏感和实用指标。
Aims: To study the changes of pHi in gastrointestinal mucosa after hypovolemic shock and resuscitation, and to provide a theoretical basis for guiding the recovery of implicit compensatory shock. METHODS: Six male goats were inflicted with hemorrhagic hypovolemic shock [mean arterial pressure 6.0 kPa (1 kPa = 7.5 mm Hg) for 1 hour by Wiggers method], rapid blood loss and 2-fold Ringer’s solution, Stomach and ileum at the stoma, respectively, into the stomach and intestinal mucosal tension meter, dynamic monitoring of gastrointestinal mucosal pHi. Results: (1) The pHi of gastrointestinal mucosa decreased progressively with the severity of shock, and restored to pre-injury 48 hours after resuscitation. (2) The change of pHi of gastrointestinal mucosa was positively correlated with the change of portal venous flow and pH, and Portal vein blood lactate and diamine oxidase content was significantly negatively correlated. Conclusion: The pHi of gastrointestinal mucosa can reflect the status of gastrointestinal mucosal ischemia and acidosis, which is a sensitive and practical indicator of implicit compensatory shock and resuscitation.