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用免疫组织化学方法对16例未完全确诊的低分化恶性肿瘤进行分析。结果表明,原疑为恶性淋巴瘤的3例,疑为间叶性恶性肿瘤的2例及癌的6例,均为Desmin,Vimentin及Myosin阳性表达,被确诊为横纹肌肉瘤,另5例原疑为癌的病例显示LCA及Vimentin阳性表达,被确诊为恶性淋巴瘤。结果提示,选用适当的标记物进行免疫组织化学标记,有助于提高低分化恶性肿瘤的诊断准确性。
16 cases of incompletely diagnosed poorly differentiated malignant tumors were analyzed by immunohistochemistry. The results showed that 3 suspected malignant lymphoma, 2 suspected malignant melanomas and 6 cancerous cancers were positive expression of Desmin, Vimentin and Myosin, were diagnosed as rhabdomyosarcoma, the other 5 cases of suspected Cases of cancer showed positive expression of LCA and Vimentin and were diagnosed as malignant lymphoma. The results suggest that the selection of appropriate markers for immunohistochemical labeling can help improve the diagnostic accuracy of poorly differentiated malignancies.