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目的探讨左旋多巴联合卡比多巴治疗儿童难治性弱视的临床疗效。方法对３６例（６３眼）４５～１４岁经遮盖治疗未愈、视力稳定６月无变化的患儿按体重予以左旋多巴（１．５ｍｇ／ｋｇ）、卡比多巴（０３８ｍｇ／ｋｇ）口服，每日３次，连续３月，观察视力、融合功能、立体视觉及网膜光敏感度、注视暗点的变化及药物的副作用。结果服药３月，６３眼弱视眼中视力提高者占８８８９％，平均提高２２７±１２６行，１０例融合功能改善，６例恢复立体视觉。视网膜光敏感度明显改善，１９眼注视暗点消失，６眼暗点缩小。基本治愈率４２８６％，副作用少。结论左旋多巴联合卡比多巴能有效地提高难治性弱视患儿的视功能，且副作用少。
Objective To investigate the clinical efficacy of levodopa combined with carbidopa in the treatment of refractory amblyopia in children. Methods Thirty six children (63 eyes) aged 4.5 to 14 years were treated with levodopa (1.5 mg / kg), carbidopa (0 0 38mg / kg) orally, 3 times a day for 3 consecutive months to observe the visual acuity, fusion function, stereo vision and retinal light sensitivity, watching dark spots and drug side effects. Results In March, 63 eyes with amblyopia accounted for 88.89% of eyesight improvement, with an average increase of 227 ± 1.26 lines, 10 cases improved fusion function and 6 cases recovered stereopsis. Retinal light sensitivity was significantly improved, 19 eyes dark spots disappeared, 6 dark spots narrowed. The basic cure rate 42 86%, fewer side effects. Conclusion Levodopa combined with carbidopa can effectively improve the visual function of children with refractory amblyopia, and less side effects.