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目的观察高压氧联合药物治疗急性脑梗死的临床效果。方法将92例符合诊断标准的脑梗死患者随机分成对照组和观察组各46例,对照组给予药物常规综合救治,观察组在对照组的基础上于发病后2～7 d内开始高压氧治疗,治疗压力为0.20～0.22 MPa,加压减压各25 min,稳压80 min,持续20 d,同时对两组治疗前后神经功能缺损的评分及治疗后有效率进行比较。结果治疗前两组患者神经功能缺损评分差异无统计学意义(P>0.05),高压氧治疗20d后,观察组神经功能缺损程度评分及有效率均较对照组改善明显(P<0.05)。结论对急性脑梗死患者采用高压氧联合药物治疗可明显降低脑卒中患者神经功能缺损程度,促进运动功能恢复,效果明显优于单纯药物治疗,且成本低,安全可靠。
Objective To observe the clinical effect of hyperbaric oxygen combined with medicine on acute cerebral infarction. Methods Ninety-two patients with cerebral infarction who met the diagnostic criteria were randomly divided into control group and observation group with 46 cases in each group. The control group was given general medical treatment. The observation group started hyperbaric oxygen therapy within 2 to 7 days after onset on the basis of the control group , Treatment pressure was 0.20 ~ 0.22 MPa, pressure and decompression for 25 min, the pressure for 80 min for 20 d, while the two groups before and after treatment of neurological deficit score and the efficiency after treatment were compared. Results There was no significant difference in neurological deficit score between the two groups before treatment (P> 0.05). After hyperbaric oxygen treatment for 20 days, the score and the effective rate of neurological deficit in the observation group were significantly improved compared with the control group (P <0.05). Conclusions The use of hyperbaric oxygen combined with medical therapy in patients with acute cerebral infarction can significantly reduce the degree of neurological deficit in patients with stroke and promote the recovery of motor function. The effect is obviously better than that of simple drug therapy, and its cost is low and safe.