To the Editor: Pediatric stroke refers to the rupture and/or occlusion of arteries or veins. It is one of the highest causes of pediatric preterm death and long?term disability. Health?care providers find dealing with pediatric stroke a challenge because of the difficult diagnosis, the lack of standard guidelines, the rapid progress, and the high mortality. In this study, we observed and analyzed the characteristics of six pediatric hemorrhage strokes complicated with interventions for congenital heart disease (CHD). We found that vascular malformation, hemodynamic fluctuation, and postoperative anticoagulant medicines were risk factors for this condition and that there was an urgent need for awareness and acknowledgment.