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目的评价序贯机械通气治疗AECOPD合并Ⅱ型呼吸衰竭的疗效。方法 AECOPD合并Ⅱ型呼吸衰竭的患者50例在常规治疗基础上插管上机用(SIMV+PSV)模式通气,在肺部感染控制窗出现后随即分为2组,序贯组27例,对照组23例。序贯组改为无创通气,对照组继续实施有创通气,以SIMV+PSV模式脱机。结果序贯治疗组有创通气时间,总机械通气时间,入住ICU时间、总住院时间比对照组明显缩短有显著差异,(P<0.05)。发生VAP例数及死亡例数与对照组有显著差异,(P<0.05)。结论序贯性机械通气治疗AECOPD合并Ⅱ型呼吸衰竭患者效果满意,是值得临床推广的治疗方法。
Objective To evaluate the efficacy of sequential mechanical ventilation in the treatment of AECOPD with type Ⅱ respiratory failure. Methods Fifty patients with AECOPD combined with type Ⅱ respiratory failure were enrolled in the mode of intubation with SIMV + PSV ventilation. After pulmonary infection control window appeared, they were divided into two groups: control group (n = 27) and control group Group of 23 cases. Sequential group changed to non-invasive ventilation, the control group continued to implement invasive ventilation, SIMV + PSV mode offline. Results In the sequential therapy group, the duration of invasive ventilation, total mechanical ventilation, ICU stay, and total hospital stay were significantly shorter than those of the control group (P <0.05). The number of VAP cases and the number of death cases were significantly different from the control group (P <0.05). Conclusions Sequential mechanical ventilation is satisfactory for patients with AECOPD complicated with type Ⅱ respiratory failure and is worthy of clinical promotion.